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A critical, unsupportive spouse isn't just a drag. That kind of mate increases the risk of major depression, researchers say. People can improve the quality of their relationships, Teo says. Interpersonal therapy and couples therapy can help identify communication problems and come up with practical improvements.

Kenichi Togawa was working at the Fukushima Dai-ichi nuclear power plant in Japan the day the earthquake and tsunami struck. His family is still living in temporary housing. For many people, the stress and isolation brought on by the disaster could pose more persistent hazards than the radiation.

A fresh analysis finds no increase in suicide among young people taking Prozac. The results add a wrinkle to the long-running debate over the safety of the medicines for the treatment of depressed young people.

The anesthetic and club drug ketamine seems to quickly lift depression symptoms. How does it work? Researchers are searching for the answer in an attempt to make a new class of depression medications.